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| Missailidis,Sotiris; Perkins,Alan; Santos-Filho,Sebastião David; Fonseca,Adenilson de Souza da; Bernardo-Filho,Mario. |
| In the continuous search for earlier diagnosis and improved therapeutic modalities against cancer, based on our constantly increasing knowledge of cancer biology, aptamers hold the promise to expand on current antibody success, but overcoming some of the problems faced with antibodies as therapeutic or delivery agents in cancer. However, as the first aptamer reached the market as an inhibitor against angiogenesis for the treatment of macular degeneration, aptamers have found only limited applications or interest in oncology, and even less as radiopharmaceuticals for diagnostic imaging and targeted radiotherapy of tumours. Yet, the chemistry for the labelling of aptamers and the options to alter their pharmacokinetic properties, to make them suitable for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aptamer; Radiopharmaceutical; Diagnostic imaging; Radiotherapy; Epithelial tumor. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700013 |
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| Trani, Tamires de Vecchi; Lyra, Natália Guerreiro; Pietroluongo, Bruno. |
| Cholesteatoma is an otologic disease, characterized as a benign aural epidermoid cyst. Clinical manifestations of this disease can be: otalgia, pain or inability to open the mouth, head tilt, facial paralysis, ataxia, and pain under temporomandibular joint palpation. Diagnosis is based on exams such as tomography, magnetic resonance imaging, and video-otoscopy; and histopathological examination is essential to confirm the diagnosis. Surgery is the most effective treatment, albeit it may not be curative, consisting of removing the remains of keratin and squamous epithelium of the middle ear. In Veterinary Medicine, this has a high rate of recurrence. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cholesteatoma; Surgery; Diagnostic imaging; Classification; Veterinary Colesteatoma; Cirurgia; Diagnóstico por imagem; Classificação; Veterinária. |
| Ano: 2019 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/37838 |
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| Moura,L.S.; Rodrigues,R.P.S.; Silva,A.B.S.; Pessoa,G.T.; Sousa,F.C.A.; Barbosa,M.A.P.S.; Souza,A.B.; Alves,J.J.R.P.; Macedo,K.V.; Diniz,A.N.; Silva,E.G.; Araújo,J.R.; Marques,D.C.; Cavalcante-Filho,M.F.; Alves,F.R.. |
| ABSTRACT Peccaries are wild mammals belonging to the Tayassu genus that are found almost everywhere in the Americas and have demonstrated great potential as an experimental model for scientific investigations. Twelve healthy adult animals were sedated to perform echocardiographic examinations in B, M and Doppler mode. The variables that exhibited statistically significant correlation coefficients with weight were LVFWd, LVIDd, LVIDs, E wave, A’RV, MAM, and TAPSE. The HR exhibited a negative relationship with the IVRT. The LA variable showed a positive correlation with the AO. The MAM exhibited correlations with the LVIDd and LVIDs. The TAPSE showed positive correlations with the E’RV and A’RV. The present study provides the first reference values for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cardiology; Wild animals; Diagnostic imaging; Heart; Hemodynamics. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100068 |
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| D’Elia,Mirella Lauria; Santos,Alice Barroso; Ribeiro,Beatriz Novaes Telles; Torres,Renato Cesar Sacchetto; Santos,Renato de Lima; Silva,Rodrigo Otávio Silveira; Nepomuceno,Anelise Carvalho. |
| ABSTRACT: A 6-year-old Fuzzy Lop rabbit was referred to a veterinary hospital with a complaint of lameness. In addition to a vertebral subluxation, two radiopaque and well-defined structures were revealed by radiographic evaluation. Ultrasonographically, the masses were characterized as parenchymal structures with diffuse mineralization and formation of reverberation artifacts, suggesting presence of gas. These two structures were excised during a laparotomy and Clostridium tertium was isolated. To the best of our knowledge, this is the first report of C. tertium infection in a pet animal. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Clostridia; Granuloma; Diagnostic imaging. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000100551 |
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| Bueno,G.M.; Girardi,A.M.; Módolo,T.J.C.; Sabes,A.F.; Oliveira,J.A.; Marques,L.C.. |
| ABSTRACT Due to the scarcity of myelogenous studies in cattle, the present study aimed to evaluate the efficacy and distribution of iopamidol and iohexol contrast agents in calves, in order to determine guidelines for obtaining diagnostic radiographs of spinal cord disorders in these animals. Ten healthy Holstein calves, seven days to two months of age, were divided into two groups, according to the contrast medium applied. Myelographic studies of the spine were performed with the calves in lateral recumbency, with radiographs repeated 20 times during a two-hour period. On the radiographs, the contrast medium was analyzed for opacity, detail of the image, distension of the medullary canal, and progression of the contrast line. After seven days, the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cattle; Diagnostic imaging; Digital radiography; Spinal cord; Spine. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401217 |
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| Prestes,Rafaela da Silveira; Santos,Flaviani Emilia dos; Souza,Izabela Patrício de; Marcelino,Sóstenes Apolo Correia; Torres,Renato Cesar Sacchetto; Malm,Christina; Freitas,Patrícia Maria Coletto; Beier,Suzane Lilian; Ecco,Roselene; Nepomuceno,Anelise Carvalho. |
| ABSTRACT: Tracheal avulsion is a condition seen in small animals and occurs as a result of a traumatic incident to the cervical and/or thoracic regions. The aim of this study is to report a case of tracheal avulsion in a cat using imaging examinations for diagnostic investigation. In this report, we examined an eight-month-old male, cat of undefined breed, diagnosed with tracheal avulsion using complementary imaging tests. This diagnosis was confirmed with post-mortem examination. Radiographic examination of the patient’s thorax and a tracheoscopy were performed. These examinations revealed complete discontinuity of the tracheal circumference, the presence of focal and circumscribed dilation of the tracheal lumen and stenosis. The patient quickly died... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diagnostic imaging; Trauma; Trachea; Veterinary pathology; Domestic cat.. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019001000603 |
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| Santos,C.J.; Valadares,R.C.; Torres,R.C.S.; Nepomuceno,A.C.. |
| ABSTRACT Portosystemic shunt (PSS) is an anomalous vascular connection between the portal venous system and the systemic circulation. These deviations connect the main portal vein (PV) or some portal branches to the vena cava (VC) or, less commonly, to the azygos vein (AV). The purpose of this case report was to describe the diagnosis of PSS in a dog classified as porto-azygos. This diagnosis is considered uncommon compared to other portosystemic shunts using ultrasonography and portography. The subject was a male dog, Yorkshire, 8 months old, presented neurological signs characterized by head press, ataxia, tremors and episodes of temporary blindness and deafness. Ultrasonographic examination revealed a dilated and curved anomalous vessel with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diagnostic imaging; Canine; Portosystemic deviatio. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300863 |
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